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The p66(Shc) adapter protein regulates the morphogenesis and epithelial maturation of fetal mouse lungs
Many signaling pathways are mediated by Shc adapter proteins that, in turn, are expressed as three isoforms with distinct functions. The p66(Shc) isoform antagonizes proliferation, regulates oxidative stress, and mediates apoptosis. It is highly expressed in the canalicular but not the later stages...
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| Hoofdauteurs: | , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Physiological Society
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3920229/ https://ncbi.nlm.nih.gov/pubmed/24375794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00062.2013 |
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