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Sphingosine-1-phosphate protects endothelial glycocalyx by inhibiting syndecan-1 shedding

Endothelial cells (ECs) are covered by a surface glycocalyx layer that forms part of the barrier and mechanosensing functions of the blood-tissue interface. Removal of albumin in bathing media induces collapse or shedding of the glycocalyx. The electrostatic interaction between arginine residues on...

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Detalhes bibliográficos
Main Authors: Zeng, Ye, Adamson, Roger H., Curry, Fitz-Roy E., Tarbell, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920139/
https://ncbi.nlm.nih.gov/pubmed/24285115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00687.2013
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