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Erythrocyte-derived sphingosine-1-phosphate stabilizes basal hydraulic conductivity and solute permeability in rat microvessels

Exogenous sphingosine-1-phosphate (S1P), a lipid mediator in blood, attenuates acute microvascular permeability increases via receptor S1P1 to stabilize the endothelium. To evaluate the contribution of erythrocytes as an endogenous source of S1P to the regulation of basal permeability, we measured p...

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Detalhes bibliográficos
Main Authors: Curry, F. E., Clark, J. F., Adamson, R. H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469701/
https://ncbi.nlm.nih.gov/pubmed/22865384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00181.2012
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