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Sphingosine-1-phosphate Maintains Normal Vascular Permeability by Preserving Endothelial Surface Glycocalyx in Intact Microvessels

OBJECTIVE: Sphingosine-1-phosphate (S1P) was found to protect the endothelial surface glycocalyx (ESG) by inhibiting matrix metalloproteinase (MMP) activity-dependent shedding of ESG in cultured endothelial cell studies. We aimed to further test that S1P contributes to the maintenance of normal vasc...

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Detalhes bibliográficos
Publicado no:Microcirculation
Main Authors: Zhang, Lin, Zeng, Min, Fan, Jie, Tarbell, John, M., Curry, Fitz-Roy E., Fu, Bingmei M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4866498/
https://ncbi.nlm.nih.gov/pubmed/27015105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/micc.12278
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