Sphingosine-1-phosphate modulation of basal permeability and acute inflammatory responses in rat venular microvessels

AIMS: Although several cultured endothelial cell studies indicate that sphingosine-1-phosphate (S1P), via GTPase Rac1 activation, enhances endothelial barriers, very few in situ studies have been published. We aimed to further investigate the mechanisms whereby S1P modulates both baseline and increa...

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Detalhes bibliográficos
Main Authors: Adamson, Roger H., Sarai, Rupinder K., Altangerel, Ariungerel, Thirkill, Twanda L., Clark, Joyce F., Curry, Fitz-Roy E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952530/
https://ncbi.nlm.nih.gov/pubmed/20542878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvq184
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