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Attenuation by sphingosine-1-phosphate of rat microvessel acute permeability response to bradykinin is rapidly reversible

To evaluate the hypothesis that sphingosine-1-phosphate (S1P) and cAMP attenuate increased permeability of individually perfused mesenteric microvessels through a common Rac1-dependent pathway, we measured the attenuation of the peak hydraulic conductivity (L(p)) in response to the inflammatory agen...

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Main Authors: Adamson, R. H., Sarai, R. K., Clark, J. F., Altangerel, A., Thirkill, T. L., Curry, F. E.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362105/
https://ncbi.nlm.nih.gov/pubmed/22427519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00614.2011
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