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Identification of Functionally Relevant Lysine Residues That Modulate Human Farnesoid X Receptor Activation
Base amino acid lysine residues play an important role in regulation of nuclear receptors [e.g., farnesyl X receptor (FXR)], leading to enhanced or suppressed biologic activity. To understand the molecular mechanisms and the subsequent effects in modulating FXR functions in diverse biologic processe...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The American Society for Pharmacology and Experimental Therapeutics
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3920091/ https://ncbi.nlm.nih.gov/pubmed/23462506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.113.084772 |
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