Enhanced expression and activity of Nox2 and Nox4 in the macula densa in ANG II-induced hypertensive mice

NAD(P)H oxidase (Nox)2 and Nox4 are the isoforms of Nox expressed in the macula densa (MD). MD-derived superoxide (O(2)(−)), primarily generated by Nox2, is enhanced by acute ANG II stimulation. However, the effects of chronic elevations in ANG II during ANG II-induced hypertension on MD-derived O(2...

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Hlavní autoři: Zhang, Jie, Chandrashekar, Kiran, Lu, Yan, Duan, Yanhua, Qu, Phillip, Wei, Jin, Juncos, Luis A., Liu, Ruisheng
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920051/
https://ncbi.nlm.nih.gov/pubmed/24285500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00515.2013
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