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Enhanced expression and activity of Nox2 and Nox4 in the macula densa in ANG II-induced hypertensive mice
NAD(P)H oxidase (Nox)2 and Nox4 are the isoforms of Nox expressed in the macula densa (MD). MD-derived superoxide (O(2)(−)), primarily generated by Nox2, is enhanced by acute ANG II stimulation. However, the effects of chronic elevations in ANG II during ANG II-induced hypertension on MD-derived O(2...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3920051/ https://ncbi.nlm.nih.gov/pubmed/24285500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00515.2013 |
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