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Telomere extension by telomerase and ALT generates variant repeats by mechanistically distinct processes
Telomeres are terminal repetitive DNA sequences on chromosomes, and are considered to comprise almost exclusively hexameric TTAGGG repeats. We have evaluated telomere sequence content in human cells using whole-genome sequencing followed by telomere read extraction in a panel of mortal cell strains...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3919612/ https://ncbi.nlm.nih.gov/pubmed/24225324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1117 |
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