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Telomere extension by telomerase and ALT generates variant repeats by mechanistically distinct processes

Telomeres are terminal repetitive DNA sequences on chromosomes, and are considered to comprise almost exclusively hexameric TTAGGG repeats. We have evaluated telomere sequence content in human cells using whole-genome sequencing followed by telomere read extraction in a panel of mortal cell strains...

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Bibliografiske detaljer
Main Authors: Lee, Michael, Hills, Mark, Conomos, Dimitri, Stutz, Michael D., Dagg, Rebecca A., Lau, Loretta M.S., Reddel, Roger R., Pickett, Hilda A.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3919612/
https://ncbi.nlm.nih.gov/pubmed/24225324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1117
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