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p190-B RhoGAP regulates the functional composition of the mesenchymal microenvironment
Hematopoiesis is regulated by components of the microenvironment, so-called niche. Here, we show that p190-B GTPase Activating Protein (p190-B) deletion in mice causes hematopoietic failure during ontogeny, in p190-B(−/−) fetal liver and bones, and in p190-B(+/−) adult bones and spleen. These defect...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3919554/ https://ncbi.nlm.nih.gov/pubmed/23563238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2013.103 |
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