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Structural basis for microtubule binding and release by dynein
Cytoplasmic dynein is a microtubule-based motor required for intracellular transport and cell division. Its movement involves coupling cycles of track binding and release with cycles of force-generating nucleotide hydrolysis. How this is accomplished given the ~25 nm separating dynein’s track- and n...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3919166/ https://ncbi.nlm.nih.gov/pubmed/22997337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1224151 |
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