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Structural basis for microtubule binding and release by dynein

Cytoplasmic dynein is a microtubule-based motor required for intracellular transport and cell division. Its movement involves coupling cycles of track binding and release with cycles of force-generating nucleotide hydrolysis. How this is accomplished given the ~25 nm separating dynein’s track- and n...

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Détails bibliographiques
Auteurs principaux: Redwine, W. B., Hernandez-Lopez, R., Zou, S., Huang, J., Reck-Peterson, S. L., Leschziner, A. E.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3919166/
https://ncbi.nlm.nih.gov/pubmed/22997337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1224151
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