In vivo mutagenesis by O6-methylguanine built into a unique site in a viral genome.
The mutagenicity of O6-methylguanine (O6MeGua), a chemical carcinogen-DNA adduct, has been studied in vivo by using a single-stranded M13mp8 genome in which a single O6MeGua residue was positioned in the unique recognition site for the restriction endonuclease Pst I. Transformation of Escherichia co...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1984
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391905/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6093094/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.20.6271 |
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