In vivo mutagenesis by O6-methylguanine built into a unique site in a viral genome.

The mutagenicity of O6-methylguanine (O6MeGua), a chemical carcinogen-DNA adduct, has been studied in vivo by using a single-stranded M13mp8 genome in which a single O6MeGua residue was positioned in the unique recognition site for the restriction endonuclease Pst I. Transformation of Escherichia co...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Loechler, E L, Green, C L, Essigmann, J M
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1984
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391905/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6093094/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.20.6271
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