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In vivo mutagenesis by O6-methylguanine built into a unique site in a viral genome.

The mutagenicity of O6-methylguanine (O6MeGua), a chemical carcinogen-DNA adduct, has been studied in vivo by using a single-stranded M13mp8 genome in which a single O6MeGua residue was positioned in the unique recognition site for the restriction endonuclease Pst I. Transformation of Escherichia co...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Loechler, E L, Green, C L, Essigmann, J M
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1984
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391905/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6093094/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.20.6271
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