Caricamento...
Human APOE genotype affects intraneuronal Aβ(1–42) accumulation in a lentiviral gene transfer model
Intraneuronal accumulation of β-amyloid (Aβ)(42) is one of the earliest pathological events in humans and in animal models of Alzheimer's disease (AD). Apolipoprotein E 4 (APOE4) is the major identified genetic risk factor for late-onset AD, with Aβ deposition beginning earlier in apoE4-positiv...
Salvato in:
| Autori principali: | , , , , , , |
|---|---|
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2014
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3919009/ https://ncbi.nlm.nih.gov/pubmed/24154541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt525 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|