IN ANTIBODY-POSITIVE FIRST-DEGREE RELATIVES OF PATIENTS WITH TYPE 1 DIABETES, HLA-A*24 AND HLA-B*18, BUT NOT HLA-B*39, ARE PREDICTORS OF IMPENDING DIABETES WITH DISTINCT HLA-DQ INTERACTIONS

AIMS/HYPOTHESIS: Secondary type 1 diabetes prevention trials require selection of participants with impending diabetes. HLA-A and -B alleles have been reported to promote disease progression. We investigated whether typing for HLA-B*18 and -B*39 may complement screening for HLA-DQ8, -DQ2 and -A*24 a...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Mbunwe, E., Van der Auwera, B. J., Weets, I., Van Crombrugge, P., Crenier, L., Coeckelberghs, M., Seret, N., Decochez, K., Vandemeulebroucke, E., Gillard, P., Keymeulen, B., van Schravendijk, C., Wenzlau, J. M., Hutton, J. C., Pipeleers, D. G., Gorus, F. K., Registry, The Belgian Diabetes
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918938/
https://ncbi.nlm.nih.gov/pubmed/23712485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-013-2951-8
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!
Laddar...

Liknande verk