IN ANTIBODY-POSITIVE FIRST-DEGREE RELATIVES OF PATIENTS WITH TYPE 1 DIABETES, HLA-A*24 AND HLA-B*18, BUT NOT HLA-B*39, ARE PREDICTORS OF IMPENDING DIABETES WITH DISTINCT HLA-DQ INTERACTIONS

AIMS/HYPOTHESIS: Secondary type 1 diabetes prevention trials require selection of participants with impending diabetes. HLA-A and -B alleles have been reported to promote disease progression. We investigated whether typing for HLA-B*18 and -B*39 may complement screening for HLA-DQ8, -DQ2 and -A*24 a...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Mbunwe, E., Van der Auwera, B. J., Weets, I., Van Crombrugge, P., Crenier, L., Coeckelberghs, M., Seret, N., Decochez, K., Vandemeulebroucke, E., Gillard, P., Keymeulen, B., van Schravendijk, C., Wenzlau, J. M., Hutton, J. C., Pipeleers, D. G., Gorus, F. K., Registry, The Belgian Diabetes
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2013
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918938/
https://ncbi.nlm.nih.gov/pubmed/23712485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-013-2951-8
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