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Artificial riboswitches for gene expression and replication control of DNA and RNA viruses

Aptazymes are small, ligand-dependent self-cleaving ribozymes that function independently of transcription factors and can be customized for induction by various small molecules. Here, we introduce these artificial riboswitches for regulation of DNA and RNA viruses. We hypothesize that they represen...

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Detalles Bibliográficos
Main Authors: Ketzer, Patrick, Kaufmann, Johanna K., Engelhardt, Sarah, Bossow, Sascha, von Kalle, Christof, Hartig, Jörg S., Ungerechts, Guy, Nettelbeck, Dirk M.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918795/
https://ncbi.nlm.nih.gov/pubmed/24449891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1318563111
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