Colorectal Carcinomas With CpG Island Methylator Phenotype 1 Frequently Contain Mutations in Chromatin Regulators

BACKGROUND & AIMS: Subgroups of colorectal carcinomas (CRCs) characterized by DNA methylation anomalies are termed CpG island methylator phenotype (CIMP)1, CIMP2, or CIMP-negative. The pathogenesis of CIMP1 colorectal carcinomas, and their effects on patients’ prognoses and responses to treatmen...

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Autori principali: Tahara, Tomomitsu, Yamamoto, Eiichiro, Madireddi, Priyanka, Suzuki, Hiromu, Maruyama, Reo, Chung, Woonbok, Garriga, Judith, Jelinek, Jaroslav, Yamano, Hiro-o, Sugai, Tamotsu, Kondo, Yutaka, Toyota, Minoru, Issa, Jean-Pierre J., Estécio, Marcos R. H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918446/
https://ncbi.nlm.nih.gov/pubmed/24211491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2013.10.060
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