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Identification of regulators of cell invasion across basement membrane in vivo

Cell invasion through basement membrane (BM) during development, immune surveillance, and metastatic cancer remains poorly understood. We have completed the first in vivo screen for regulators of cell invasion through BM, using the simple model of C. elegans anchor cell invasion, and identified 99 g...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Matus, David Q., Li, Xiao-Yan, Durbin, Sarah, Agarwal, Daniel, Chi, Qiuyi, Weiss, Stephen J., Sherwood, David R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3917318/
https://ncbi.nlm.nih.gov/pubmed/20442418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2000654
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