Forces drive basement membrane invasion in Caenorhabditis elegans

During invasion, cells breach basement membrane (BM) barriers with actin-rich protrusions. It remains unclear, however, whether actin polymerization applies pushing forces to help break through BM, or whether actin filaments play a passive role as scaffolding for targeting invasive machinery. Here,...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Cáceres, Rodrigo, Bojanala, Nagagireesh, Kelley, Laura C., Dreier, Jes, Manzi, John, Di Federico, Fahima, Chi, Qiuyi, Risler, Thomas, Testa, Ilaria, Sherwood, David R., Plastino, Julie
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2018
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233148/
https://ncbi.nlm.nih.gov/pubmed/30348801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1808760115
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