A dosage-dependent pleiotropic role of Dicer in prostate cancer growth and metastasis

Dicer is as an RNase III enzyme essential for the maturation of the majority of microRNAs. Recent studies have revealed down-regulation or hemizygous loss of Dicer in many tumor models and demonstrated that suppressing Dicer activity enhances tumorigenic activities of lung and breast cancer cells, w...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Zhang, Boyu, Chen, Hua, Zhang, Li, Dakhova, Olga, Zhang, Yiqun, Lewis, Michael T, Creighton, Chad J, Ittmann, Michael M, Xin, Li
Formato: Artigo
Idioma:Inglês
Publicado: 2013
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916938/
https://ncbi.nlm.nih.gov/pubmed/23851498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.281
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares