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Dicer Ablation Impairs Prostate Stem Cell Activity and Causes Prostate Atrophy

Dicer is an RNase III enzyme essential for microRNA maturation. Dicer ablation in diverse tissues has been shown to block tissue differentiation, induce cell apoptosis, impair specialized cellular function, and perturb organ structures. To gain insight into the role of microRNAs in prostate tissue f...

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Detalhes bibliográficos
Main Authors: Zhang, Li, Zhang, Boyu, Valdez, Joseph M., Wang, Fen, Ittmann, Michael, Xin, Li
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030968/
https://ncbi.nlm.nih.gov/pubmed/20517984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.455
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