ROCK Inhibitor Y-27632 Suppresses Dissociation-Induced Apoptosis of Murine Prostate Stem/Progenitor Cells and Increases Their Cloning Efficiency

Activation of the RhoA/ROCK signaling pathway has been shown to contribute to dissociation-induced apoptosis of embryonic and neural stem cells. We previously demonstrated that approximately 1 out of 40 Lin(−)Sca-1(+)CD49f(high) (LSC) prostate basal epithelial cells possess the capacities of stem ce...

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Detalhes bibliográficos
Main Authors: Zhang, Li, Valdez, Joseph M., Zhang, Boyu, Wei, Lei, Chang, Jiang, Xin, Li
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065488/
https://ncbi.nlm.nih.gov/pubmed/21464902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018271
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