Function of phosphorylation of NF-kB p65 ser536 in prostate cancer oncogenesis

Majority of prostate cancer (PCa) patients carry TMPRSS2/ERG (T/E) fusion genes and there has been tremendous interest in understanding how the T/E fusion may promote progression of PCa. We showed that T/E fusion can activate NF-kB pathway by increasing phosphorylation of NF-kB p65 Ser536 (p536), bu...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhang, Li, Shao, Longjiang, Creighton, Chad J., Zhang, Yiqun, Xin, Li, Ittmann, Michael, Wang, Jianghua
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467437/
https://ncbi.nlm.nih.gov/pubmed/25749044
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