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RNAi Factors are Present and Active in Human Cell Nuclei

RNAi is widely appreciated as a powerful regulator of mRNA translation in the cytoplasm of mammalian cells. However, the presence and activity of RNAi factors in the mammalian nucleus has been the subject of considerable debate. Here we show that Argonaute-2 (Ago2) and RNAi factors Dicer, TRBP and T...

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Detalhes bibliográficos
Main Authors: Gagnon, Keith T., Li, Liande, Chu, Yongjun, Janowski, Bethany A., Corey, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916906/
https://ncbi.nlm.nih.gov/pubmed/24388755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.12.013
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