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Stable association of RNAi machinery is conserved between the cytoplasm and nucleus of human cells

Argonaute 2 (AGO2), the catalytic engine of RNAi, is typically associated with inhibition of translation in the cytoplasm. AGO2 has also been implicated in nuclear processes including transcription and splicing. There has been little insight into AGO2's nuclear interactions or how they might di...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Kalantari, Roya, Hicks, Jessica A., Li, Liande, Gagnon, Keith T., Sridhara, Viswanadham, Lemoff, Andrew, Mirzaei, Hamid, Corey, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4911916/
https://ncbi.nlm.nih.gov/pubmed/27198507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.056499.116
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