The development and validation of an LC-MS/MS method for the determination of a new anti-malarial compound (TK900D) in human whole blood and its application to pharmacokinetic studies in mice

BACKGROUND: Malaria is one of the most lethal and life-threatening killer infectious diseases in the world, and account for the deaths of more than half a million people annually. Despite the remarkable achievement made in preventing and eradicating malaria, it still remains a threat to the public h...

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Autors principals: Abay, Efrem T, van der Westhuizen, Jan H, Swart, Kenneth J, Gibhard, Liezl, Tukulula, Matshawandile, Chibale, Kelly, Wiesner, Lubbe
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Methodology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916804/
https://ncbi.nlm.nih.gov/pubmed/24484513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-13-42
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