Evolutionary and Structural Analyses of Mammalian Haloacid Dehalogenase-type Phosphatases AUM and Chronophin Provide Insight into the Basis of Their Different Substrate Specificities

Mammalian haloacid dehalogenase (HAD)-type phosphatases are an emerging family of phosphatases with important functions in physiology and disease, yet little is known about the basis of their substrate specificity. Here, we characterize a previously unexplored HAD family member (gene annotation, pho...

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Detaylı Bibliyografya
Asıl Yazarlar: Seifried, Annegrit, Knobloch, Gunnar, Duraphe, Prashant S., Segerer, Gabriela, Manhard, Julia, Schindelin, Hermann, Schultz, Jörg, Gohla, Antje
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2014
Konular:
Enzymology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916544/
https://ncbi.nlm.nih.gov/pubmed/24338473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.503359
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