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Chronophin Dimerization Is Required for Proper Positioning of Its Substrate Specificity Loop
Mammalian phosphatases of the haloacid dehalogenase (HAD) superfamily have emerged as important regulators of physiology and disease. Many of these enzymes are stable homodimers; however, the role of their dimerization is largely unknown. Here, we explore the function of the obligatory homodimerizat...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3908439/ https://ncbi.nlm.nih.gov/pubmed/24338687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.536482 |
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