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Chronophin Dimerization Is Required for Proper Positioning of Its Substrate Specificity Loop

Mammalian phosphatases of the haloacid dehalogenase (HAD) superfamily have emerged as important regulators of physiology and disease. Many of these enzymes are stable homodimers; however, the role of their dimerization is largely unknown. Here, we explore the function of the obligatory homodimerizat...

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Main Authors: Kestler, Christian, Knobloch, Gunnar, Tessmer, Ingrid, Jeanclos, Elisabeth, Schindelin, Hermann, Gohla, Antje
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3908439/
https://ncbi.nlm.nih.gov/pubmed/24338687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.536482
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