Combining NK cells and mAb9.2.27 to combat NG2-dependent and anti-inflammatory signals in glioblastoma

Glioblastoma is a deadly brain cancer with limited treatment options. Targeting chondroitin sulfate proteoglycan 4 (CSPG4, best known as NG2) with the monoclonal antibody mAb9.2.27 and activated natural killer (NK) cells abrogated the tumor growth and prolonged the survival of glioblastoma-bearing a...

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Hauptverfasser: Kmiecik, Justyna, Gras Navarro, Andrea, Poli, Aurelie, Planagumà, Jesús Planagumà, Zimmer, Jacques, Chekenya, Martha
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916357/
https://ncbi.nlm.nih.gov/pubmed/24575382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.27185
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