Lsm2 and Lsm3 bridge the interaction of the Lsm1-7 complex with Pat1 for decapping activation

The evolutionarily conserved Lsm1-7-Pat1 complex is the most critical activator of mRNA decapping in eukaryotic cells and plays many roles in normal decay, AU-rich element-mediated decay, and miRNA silencing, yet how Pat1 interacts with the Lsm1-7 complex is unknown. Here, we show that Lsm2 and Lsm3...

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Autores principales: Wu, Donghui, Muhlrad, Denise, Bowler, Matthew W, Jiang, Shimin, Liu, Zhou, Parker, Roy, Song, Haiwei
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2014
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3915908/
https://ncbi.nlm.nih.gov/pubmed/24247251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.152
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