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QSAR study on maximal inhibition (I(max)) of quaternary ammonium antagonists for S-(−)-nicotine-evoked dopamine release from dopaminergic nerve terminals in rat striatum
Maximal inhibition (I(max)) of the agonist effect is an important pharmacological property of inhibitors that interact with multiple receptor subtypes that are activated by the same agonist and which elicit the same functional response. This report represents the first QSAR study on a set of 66 mono...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3914672/ https://ncbi.nlm.nih.gov/pubmed/19477134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.05.010 |
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