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QSAR study on maximal inhibition (I(max)) of quaternary ammonium antagonists for S-(−)-nicotine-evoked dopamine release from dopaminergic nerve terminals in rat striatum

Maximal inhibition (I(max)) of the agonist effect is an important pharmacological property of inhibitors that interact with multiple receptor subtypes that are activated by the same agonist and which elicit the same functional response. This report represents the first QSAR study on a set of 66 mono...

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Detalhes bibliográficos
Main Authors: Zheng, Fang, McConnell, Matthew J., Zhan, Chang-Guo, Dwoskin, Linda P., Crooks, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3914672/
https://ncbi.nlm.nih.gov/pubmed/19477134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.05.010
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