QSAR study on maximal inhibition (I(max)) of quaternary ammonium antagonists for S-(−)-nicotine-evoked dopamine release from dopaminergic nerve terminals in rat striatum

Maximal inhibition (I(max)) of the agonist effect is an important pharmacological property of inhibitors that interact with multiple receptor subtypes that are activated by the same agonist and which elicit the same functional response. This report represents the first QSAR study on a set of 66 mono...

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Hlavní autoři: Zheng, Fang, McConnell, Matthew J., Zhan, Chang-Guo, Dwoskin, Linda P., Crooks, Peter A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3914672/
https://ncbi.nlm.nih.gov/pubmed/19477134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.05.010
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