Therapeutic Targeting of Oncogenic K-Ras by a Covalent Catalytic Site Inhibitor

Eitemau Tebyg

• Synthesis and structure activity relationships of a series of 4-amino-1H-pyrazoles as covalent inhibitors of CDK14
  gan: Ferguson, Fleur M., et al.
  Cyhoeddwyd: (2019)
• In situ selectivity profiling and crystal structure of SML-8-73-1, an active site inhibitor of oncogenic K-Ras G12C
  gan: Hunter, John C., et al.
  Cyhoeddwyd: (2014)
• Development of small molecules targeting the pseudokinase Her3
  gan: Lim, Sang Min, et al.
  Cyhoeddwyd: (2015)
• Discovery of covalent CDK14 inhibitors with pan-TAIRE family specificity
  gan: Ferguson, Fleur M., et al.
  Cyhoeddwyd: (2019)
• Discovery of potent and selective covalent inhibitors of JNK
  gan: Zhang, Tinghu, et al.
  Cyhoeddwyd: (2012)