Granzyme A is critical for recovery of mice from infection with the natural cytopathic viral pathogen, ectromelia.

Cytolytic lymphocytes are of cardinal importance in the recovery from primary viral infections. Both natural killer cells and cytolytic T cells mediate at least part of their effector function by target cell lysis and DNA fragmentation. Two proteins, perforin and granzyme B, contained within the cyt...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Müllbacher, A, Ebnet, K, Blanden, R V, Hla, R T, Stehle, T, Museteanu, C, Simon, M M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39138/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8650169/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.12.5783
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