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Morphine Regulates Expression of μ-Opioid Receptor MOR-1A, an Intron-Retention Carboxyl Terminal Splice Variant of the μ-Opioid Receptor (OPRM1) Gene via miR-103/miR-107

The μ-opioid receptor (MOR-1) gene OPRM1 undergoes extensive alternative splicing, generating an array of splice variants. Of these variants, MOR-1A, an intron-retention carboxyl terminal splice variant identical to MOR-1 except for the terminal intracellular tail encoded by exon 3b, is quite abunda...

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Detalhes bibliográficos
Main Authors: Lu, Zhigang, Xu, Jin, Xu, Mingming, Pasternak, Gavril W., Pan, Ying-Xian
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913361/
https://ncbi.nlm.nih.gov/pubmed/24302561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.113.089292
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