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The role of miR-103 and miR-107 in regulation of CDK5R1 expression and in cellular migration.
CDK5R1 encodes p35, a specific activator of the serine/threonine kinase CDK5, which plays crucial roles in CNS development and maintenance. CDK5 activity strongly depends on p35 levels and p35/CDK5 misregulation is deleterious for correct CNS function, suggesting that a tightly controlled regulation...
Tallennettuna:
| Päätekijät: | , , , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Public Library of Science (PLoS)
2011-01-01
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| Sarja: | PLoS ONE |
| Linkit: | http://europepmc.org/articles/PMC3100319?pdf=render |
| Tagit: |
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