MG132 Ameliorates Kidney Lesions by Inhibiting the Degradation of Smad7 in Streptozotocin-Induced Diabetic Nephropathy

Background. Smad7 is the main negative regulatory protein in the transforming growth factor-β (TGF-β) downstream signaling pathway, which plays an important role in diabetic nephropathy (DN) and may be related to the ubiquitin proteasome pathway (UPP). Aim. We investigated the role of UPP in regulat...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Gao, Chenlin, Aqie, Keri, Zhu, Jianhua, Chen, Guo, Xu, Ling, Jiang, Lan, Xu, Yong
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913347/
https://ncbi.nlm.nih.gov/pubmed/24511554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/918396
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky