Llwytho...

Inter-residue coupling contributes to high-affinity subtype-selective binding of α-bungarotoxin to nicotinic receptors

The crystal structure of a pentameric α7 ligand-binding domain chimaera with bound α-btx (α-bungarotoxin) showed that of the five conserved aromatic residues in α7, only Tyr(184) in loop C of the ligand-binding site was required for high-affinity binding. To determine whether the contribution of Tyr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sine, Steven M., Huang, Sun, Li, Shu-Xing, daCOSTA, Corrie J. B., Chen, Lin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912756/
https://ncbi.nlm.nih.gov/pubmed/23802200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20130638
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