Lanean...

p53 promotes repair of heterochromatin DNA by regulating JMJD2b and SUV39H1 expression

Constitutive heterochromatin is important for maintaining chromosome stability but also delays the repair of DNA double strand breaks (DSB). DSB repair in complex mammalian genomes involves a fast phase (2–6 hrs) where most of the breaks are rapidly repaired, and a slow phase (up to 24 hrs) where th...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zheng, Hong, Chen, Lihong, Pledger, W. Jack, Fang, Jia, Chen, Jiandong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912226/
https://ncbi.nlm.nih.gov/pubmed/23376847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.6
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!