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Temporal Dynamics of Glyoxalase 1 in Secondary Neuronal Injury
BACKGROUND: Enhanced glycolysis leads to elevated levels of the toxic metabolite methylglyoxal which contributes to loss of protein-function, metabolic imbalance and cell death. Neurons were shown being highly susceptible to methylglyoxal toxicity. Glyoxalase 1 as an ubiquitous enzyme reflects the m...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3911945/ https://ncbi.nlm.nih.gov/pubmed/24498315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087364 |
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