Temporal Dynamics of Glyoxalase 1 in Secondary Neuronal Injury

BACKGROUND: Enhanced glycolysis leads to elevated levels of the toxic metabolite methylglyoxal which contributes to loss of protein-function, metabolic imbalance and cell death. Neurons were shown being highly susceptible to methylglyoxal toxicity. Glyoxalase 1 as an ubiquitous enzyme reflects the m...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Pieroh, Philipp, Koch, Marco, Wagner, Daniel-Christoph, Boltze, Johannes, Ehrlich, Angela, Ghadban, Chalid, Hobusch, Constance, Birkenmeier, Gerd, Dehghani, Faramarz
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2014
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911945/
https://ncbi.nlm.nih.gov/pubmed/24498315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087364
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg