Intrinsic Up-Regulation of 2-AG Favors an Area Specific Neuronal Survival in Different In Vitro Models of Neuronal Damage

BACKGROUND: The endocannabinoid 2-arachidonoyl glycerol (2-AG) acts as a retrograde messenger and modulates synaptic signaling e. g. in the hippocampus. 2-AG also exerts neuroprotective effects under pathological situations. To better understand the mechanism beyond physiological signaling we used O...

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Main Authors: Kallendrusch, Sonja, Hobusch, Constance, Ehrlich, Angela, Nowicki, Marcin, Ziebell, Simone, Bechmann, Ingo, Geisslinger, Gerd, Koch, Marco, Dehghani, Faramarz
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527460/
https://ncbi.nlm.nih.gov/pubmed/23284665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051208
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