Residues Arg703, Asp777, and Arg781 of the RNase H Domain of Hepatitis B Virus Polymerase Are Critical for Viral DNA Synthesis

Hepatitis B virus (HBV) synthesizes its DNA genome through reverse transcription, which is catalyzed by viral polymerase (Pol). Previous studies suggested that the RNase H domain of hepadnaviral Pol may contribute to multiple steps of the viral genome replication, such as RNA encapsidation and viral...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Ko, Chunkyu, Shin, Youn-Chul, Park, Woo-Jin, Kim, Seungtaek, Kim, Jonghwa, Ryu, Wang-Shick
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
Genome Replication and Regulation of Viral Gene Expression
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911735/
https://ncbi.nlm.nih.gov/pubmed/24131721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01916-13
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky