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Four Conserved Cysteine Residues of the Hepatitis B Virus Polymerase Are Critical for RNA Pregenome Encapsidation

Hepadnaviruses replicate via reverse transcription of an RNA template, the pregenomic RNA (pgRNA). Although hepadnaviral polymerase (Pol) and retroviral reverse transcriptase are distantly related, some of their features are distinct. In particular, Pol contains two additional N-terminal subdomains,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kim, Seahee, Lee, Jehan, Ryu, Wang-Shick
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715788/
https://ncbi.nlm.nih.gov/pubmed/19515776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00332-09
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