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Four Conserved Cysteine Residues of the Hepatitis B Virus Polymerase Are Critical for RNA Pregenome Encapsidation

Hepadnaviruses replicate via reverse transcription of an RNA template, the pregenomic RNA (pgRNA). Although hepadnaviral polymerase (Pol) and retroviral reverse transcriptase are distantly related, some of their features are distinct. In particular, Pol contains two additional N-terminal subdomains,...

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Библиографические подробности
Главные авторы: Kim, Seahee, Lee, Jehan, Ryu, Wang-Shick
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2009
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715788/
https://ncbi.nlm.nih.gov/pubmed/19515776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00332-09
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