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DDB1 Stimulates Viral Transcription of Hepatitis B Virus via HBx-Independent Mechanisms

HBx, a small regulatory protein of hepatitis B virus (HBV), augments viral DNA replication by stimulating viral transcription. Among numerous reported HBx-binding proteins, DDB1 has drawn attention, because DDB1 acts as a substrate receptor of the Cul4-DDB1 ubiquitin E3 ligase. Previous work reporte...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Kim, Woohyun, Lee, Sooyoung, Son, Yeongnam, Ko, Chunkyu, Ryu, Wang-Shick
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068517/
https://ncbi.nlm.nih.gov/pubmed/27535046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00977-16
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